Letter | Published:

Effect of Particle Size on Blood Griseofulvin-Levels in Man

Naturevolume 193pages588589 (1962) | Download Citation

Subjects

Abstract

FOR some drugs both the degree of alimentary absorption and the consequent levels in the blood are inversely related to particle size. Here we summarize the results of experiments to investigate the relationship between the particle-size of griseofulvin and its level in the blood after oral administration of the drug.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Gooden, E. L., and Smith, C. M., Indust. Eng. Chem. (Anal. Ed.), 12, 479 (1940).

  2. 2

    Bedford, C., Child, K. J., and Tomich, E. G., Nature, 184, 364 (1959).

Download references

Author information

Affiliations

  1. Glaxo Laboratories, Greenford Road, Greenford, Middlesex

    • R. M. ATKINSON
    • , CAROLE BEDFORD
    • , K. J. CHILD
    •  & E. G. TOMICH

Authors

  1. Search for R. M. ATKINSON in:

  2. Search for CAROLE BEDFORD in:

  3. Search for K. J. CHILD in:

  4. Search for E. G. TOMICH in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/193588a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.