Letter | Published:

Susceptibility of Mycoplasma (Pleuropneumonia-like Organisms) and Bacterial Protoplasts to Lysis by Various Agents

Naturevolume 193pages502503 (1962) | Download Citation



THE Mycoplasma organisms (pleuropneumonia-like organisms, PPLO) are limited by a thin and plastic cell envelope1. The absence of diaminopimelic acid and hexosamines in Mycoplasma2,3 indicates the absence of the ‘mucopeptide complex’ from their cell envelope. The thickness of the Mycoplasma cell envelope was found to be 75 Å.1, which is similar to that of the cytoplasmic membrane of bacteria4. These findings might indicate that the Mycoplasma have no cell wall and are limited only by a membrane resembling the cytoplasmic membrane of bacterial protoplasts. In order to elucidate this point, a comparative study of some of the properties of the Mycoplasma organisms and bacterial protoplasts was carried out.

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  1. Department of Clinical Microbiology, Hebrew University-Hadassah Medical School, Jerusalem

    • S. RAZIN
    •  & M. ARGAMAN


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