Abstract
IN 1960, Axelrod1 found N-methyladrenaline in adrenal glands of several animals and a large quantity of N-methylmetadrenaline in the urine from the rat administered with N-methyladrenaline. On these findings a new metabolic pathway of adrenaline involving its N-methylation was suggested. The possibility of this new pathway of adrenaline in human beings has been investigated.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Axelrod, J., Biochim. Biophys. Acta, 45, 614 (1960).
Yoshinaga, K., Itoh, C., Sato, T., Ishida, N., and Wada, Y., Nature, 191, 599 (1961).
Yoshinaga, E., Itoh, C., Sato, N., Ishida, N., and Wada, Y., Tohoku J. Exp. Med., 74, 105 (1961).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ITOH, C., YOSHINAGA, K., SATO, T. et al. Presence of N-Methylmetadrenaline in Human Urine and Tumour Tissue of Phæochromocytoma. Nature 193, 477–478 (1962). https://doi.org/10.1038/193477b0
Issue Date:
DOI: https://doi.org/10.1038/193477b0
This article is cited by
-
Orientierende Übersicht
Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie (1966)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.