Abstract
WE wish to report a simple method for obtaining highly purified anti-thyroglobulin antibodies. We are prompted to communicate our findings because of the interest at present in thyroglobulin antibodies—particularly with respect to human ‘auto-immune’ disease; the fact that the purification of these antibodies has not been previously described; and finally because of the ease with which good yields of purified antibody may be obtained.
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References
Edelhoch, H., J. Biol. Chem., 235, 1326 (1960).
Charlwood, P. A., Biochem. J., 73, 126 (1958).
Jirgenson, B., Arch. Biochem. and Biophys., 48, 154 (1954). Jirgenson, B., and Sirotzky, S., J. Amer. Chem. Soc., 76, 1364 (1954).
Yang, J. T., and Foster, J. F., J. Amer. Chem. Soc., 77, 2374 (1955).
Singer, S. J., Eggman, L., and Campbell, D. H., J. Amer. Chem. Soc., 77, 4851 (1955), Singer, S. J., and Campbell, D. H., ibid., 77, 3499 (1955).
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METZGER, H., EDELHOCH, H. Purification of Anti-Thyroglobin Antibodies. Nature 193, 275–276 (1962). https://doi.org/10.1038/193275a0
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DOI: https://doi.org/10.1038/193275a0
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