Letter | Published:

Allergy to a Carbon-Functional Organic Silicon Compound, Dimethyldi-(4-hydroxyphenyl)-silane

Naturevolume 192pages989990 (1961) | Download Citation



THE noxious effects of certain inorganic silicon compounds are well known1. Polymeric organic silicon compounds, on the contrary, are chemically very inert and show a low toxicity2. Some organic silicon compounds may, however, produce toxic effects3.

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  1. 1

    Holt, P. F., Pneumoconiosis (Edward Arnold, Publishers, Ltd., London, 1957).

  2. 2

    McGregor, R. R., Silicones in Medicine and Surgery (distributed by Dow Corning Corporation, 1957).

  3. 3

    Eaborn, C., Organosilicon Compounds, 473 (Butterworths Scientific Publications, London, 1960).

  4. 4

    Rochow, E. G., An Introduction to the Chemistry of the Silicones, 1 (John Wiley and Sons, Inc., New York, 1951).

  5. 5

    Speier, J. L., J. Amer. Chem. Soc., 74, 1003 (1952). Speier, Dow Corning Corporation, Midland, Michigan, who synthesized dimethyldi-(4-hydroxyphenyl)-silane, kindly supplied a sample.

  6. 6

    Fregert, S., and Rorsman, H., Acta Dermat.-Venereol., 40, 206 (1960).

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  1. Department of Dermatology, University of Lund



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