Letter | Published:

Release of Noradrenaline from the Spleen of the Cat by Acetylcholine

Naturevolume 192pages880881 (1961) | Download Citation


  • An Erratum to this article was published on 10 February 1962


ACETYLCHOLINE contracts the spleen of the dog1 and cat2. In these species the effect of acetylcholine in contracting the spleen is not blocked by atropine, but is blocked by dibenzyline and reduced by prior treatment of the animal with reserpine; thus it appears that the action of acetylcholine may be mediated by releasing noradrenaline from its stores in the spleen, which afterwards causes a contraction. The work reported here provides further evidence that acetylcholine liberates noradrenaline from the cat spleen.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Daly, M. de B., and Scott, M. J., J. Physiol., 156, 246 (1961).

  2. 2

    Brandon, K. W., and Rand, M. J., J. Physiol., 157, 18 (1961).

  3. 3

    Brown, G. L., and Gillespie, J. S., J. Physiol., 138, 81 (1957).

  4. 4

    Pennefather, J. N., and Rand, M. J., J. Physiol., 154, 277 (1961).

  5. 5

    Boyd, H., Chang, V., and Rand, M. J., Brit. J. Pharmacol., 15, 525 (1960).

  6. 6

    Burn, J. H., and Rand, M. J., J. Physiol., 147, 135 (1959).

Download references

Author information

Author notes


    Present address: Department of Zoology, University of Melbourne, Victoria, Australia


  1. Department of Pharmacology, University of Sydney, New South Wales

    • K. W. BRANDON
    •  & HELEN BOYD


  1. Search for K. W. BRANDON in:

  2. Search for HELEN BOYD in:

About this article

Publication history

Issue Date




By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.