Letter | Published:

Morphological Changes following Transplantation and Chronic Obstruction of the Rabbit Appendix

Nature volume 192, pages 877878 (02 December 1961) | Download Citation



EXPERIMENTS reported by Sholpo1 from the Moscow Medical Institute are claimed to be evidence in support of the theory that morphology and function depend on environment. In a series of 46 animal experiments Sholpo transplanted the rabbit cæcal appendix to various sites in the small bowel, almost all in the ileum. After three months the transplanted appendices showed marked reduction in the size of the lymphoid tissue. The results were summarized as follows:

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  1. 1.

    , Ark. Anat. Gistol. Embriol., 35, 59 (1958).

  2. 2.

    , , and , Brit. J. Exp. Path., 42, 153 (1961).

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    • J. A. WILLIAMS

    present address: Department of Surgery, Queen Elizabeth Hospital, Birmingham 15.


  1. Department of Surgery, University of Minnesota Medical School, Minneapolis.

    • J. A. WILLIAMS
    • , W. O. GRIFFEN JUN.
    •  & A. SHARMA


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