Letter | Published:

Identification of the Chromosome Complements of New-born and Adult Living Mice

Naturevolume 192pages13161317 (1961) | Download Citation



CHROMOSOME abnormalities similar to those known in man are now being found in mice1. Identification of the chromosome complement of these mice in cells from bone marrow2 or corneal epithelium3 involved the death of the animals. The advantage in identifying the chromosome complement of living mice is obvious, and the present communication describes techniques to achieve this in new-born and in adult mice, chiefly by the use of primary outgrowths of cells from pieces of tissue cultured in vitro.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Welshons, W. J., and Russell, L. B., Proc. U.S. Nat. Acad. Sci., 45, 560 (1959). Cattanach, B. M., Genet. Res. Camb., 2, 156 (1961).

  2. 2

    Ford, C. E., and Hamerton, J. L., Stain Tech., 31, 247 (1956).

  3. 3

    Fechheimer, N. S., Nature, 188, 247 (1960).

  4. 4

    Hsu, T. C., and Klatt, O., J. Nat. Cancer Inst., 21, 437 (1958). Rothfels, K. H., and Siminovitch, L., Stain Tech., 33, 73 (1958).

Download references

Author information


  1. Division of Experimental Biology, National Institute for Medical Research, Mill Hill, London, N.W.7

    • R. G. EDWARDS


  1. Search for R. G. EDWARDS in:

About this article

Publication history

Issue Date




By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.