Letter | Published:

Identification of the Chromosome Complements of New-born and Adult Living Mice

Nature volume 192, pages 13161317 (30 December 1961) | Download Citation

Subjects

Abstract

CHROMOSOME abnormalities similar to those known in man are now being found in mice1. Identification of the chromosome complement of these mice in cells from bone marrow2 or corneal epithelium3 involved the death of the animals. The advantage in identifying the chromosome complement of living mice is obvious, and the present communication describes techniques to achieve this in new-born and in adult mice, chiefly by the use of primary outgrowths of cells from pieces of tissue cultured in vitro.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , and , Proc. U.S. Nat. Acad. Sci., 45, 560 (1959). , Genet. Res. Camb., 2, 156 (1961).

  2. 2.

    , and , Stain Tech., 31, 247 (1956).

  3. 3.

    , Nature, 188, 247 (1960).

  4. 4.

    , and , J. Nat. Cancer Inst., 21, 437 (1958). , and , Stain Tech., 33, 73 (1958).

Download references

Author information

Affiliations

  1. Division of Experimental Biology, National Institute for Medical Research, Mill Hill, London, N.W.7.

    • R. G. EDWARDS

Authors

  1. Search for R. G. EDWARDS in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/1921316a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.