Letter | Published:

Serological Evidence of a Chromatographic Sub-fractionation of Human 7S γ-Globulin

Nature volume 192, pages 13011302 (30 December 1961) | Download Citation



PREPARATIONS consisting of the electrophoretically slowest migrating part of the 7S γ-globulin were prepared by means of preparative zone electrophoresis. Individual preparations were obtained from normal serum and from the serum of an Rh-immunized individual. Preparations from pooled plasma were obtained from commercially available Cohn fractionated γ-globulin (supplied by AB KABI, Stockholm). All preparations showed Gm(a+) character when tested in a serum-grouping system according to Grubb1,2. On immunoelectrophoresis with different rabbit antisera against human whole serum (supplied by Behringwerke, W. Germany) the γ-globulin preparations showed the character of 7S γ-globulin. No β2A or β2M was present.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    , Acta Path. Microbiol. Scand., 39, 195 (1956).

  2. 2.

    , and , Acta Path. Microbiol. Scand., 39, 390 (1956).

  3. 3.

    , Biochim. Biophys. Acta, 31, 216 (1959).

  4. 4.

    , Les globulines sériques du systéme gamma, 119 (Editions Arscia, S.A., Bruxelles, 1960).

  5. 5.

    , , , and , J. Clin. Invest., 40, 117 (1961).

Download references

Author information


  1. Department of Clinical Chemistry, University of Uppsala.



  1. Search for ULF NILSSON in:

About this article

Publication history





By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.