Letter | Published:

Serological Evidence of a Chromatographic Sub-fractionation of Human 7S γ-Globulin

Nature volume 192, pages 13011302 (30 December 1961) | Download Citation

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Abstract

PREPARATIONS consisting of the electrophoretically slowest migrating part of the 7S γ-globulin were prepared by means of preparative zone electrophoresis. Individual preparations were obtained from normal serum and from the serum of an Rh-immunized individual. Preparations from pooled plasma were obtained from commercially available Cohn fractionated γ-globulin (supplied by AB KABI, Stockholm). All preparations showed Gm(a+) character when tested in a serum-grouping system according to Grubb1,2. On immunoelectrophoresis with different rabbit antisera against human whole serum (supplied by Behringwerke, W. Germany) the γ-globulin preparations showed the character of 7S γ-globulin. No β2A or β2M was present.

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Affiliations

  1. Department of Clinical Chemistry, University of Uppsala.

    • ULF NILSSON

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DOI

https://doi.org/10.1038/1921301a0

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