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Pharmacodynamical Effects of Asarone and β-Asarone

Naturevolume 192pages12991300 (1961) | Download Citation



DANDIYA et al.1,2 have determined the effect on the central nervous system of Acorus calamus, a drug used in the Indian system of medicine for various ailments including some of the mental disorders. In the present work two fractions ‘asarone’ and ‘β-asarone’ (isolated by Baxter and Kandel) of the volatile oil of Acorus calamus have been investigated with regard to effects on the central nervous system and other pharmacodynamical actions which these drugs have.

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  1. 1

    Dandiya, P. C., and Cullumbine, H., Arch. Int. Pharmacodyn., 125, 353 (1959).

  2. 2

    Dandiya, P. C., Cullumbine, H., and Sellers, E. A., Arch. Int. Pharmacodyn., 126, 334 (1959).

  3. 3

    Norton, Stata, and de Bear, E. J., Ann. N.Y. Acad. Sci., 65, 249 (1956).

  4. 4

    Maffii, G., J. Pharm. Pharmacol., 11, 129 (1959).

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  1. Department of Pharmacology, S.M.S. Medical College, Jaipur, India

    • J. D. SHARMA
    •  & P. C. DANDIYA
  2. Faculty of Pharmacy, University of Toronto

    • R. M. BAXTER
    •  & S. I. KANDEL


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