Letter | Published:

Erythrocyte Cholinesterase-levels in Mental Patients

Naturevolume 192page1216 (1961) | Download Citation

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Abstract

RUBIN has published data1a on erythrocyte acetyl-cholinesterase which showed a bimodal distribution of this enzyme in schizophrenic patients. This paper was criticized1b and the criticism answered1c. Our work was an attempt to repeat Rubin's findings in larger groups of patients and normals.

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References

  1. 1

    a, Rubin, L. S., Science, 128, 254 (1958); b, Krech, D., Rosenzweig, M. R., and Bennett, E. L., ibid., 128, 1176 (1958). c, Rubin, L. S., ibid., 128, 1176 (1958).

  2. 2

    Ellman, G. L., Courtney, K. D., Andres, jun., V., and Featherstone, R. M., Biochem. Pharmacol., 7, 88 (1961).

  3. 3

    Wright, C. I., and Sabine, J. C., J. Pharm. Exp. Therap., 93, 230 (1948).

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    Sabine, J. C., Blood, 10, 1132 (1955).

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    Sawitsky, A., Fitch, H. M., and Meyer, L. M., J. Lab. Clin. Med., 33, 203 (1948).

  6. 6

    Kety, S., Science, 129, 1528 (1959).

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Affiliations

  1. Langley-Porter Neuropsychiatric Institute, San Francisco, 22, California

    • GEORGE L. ELLMAN
    •  & ENOCH CALLAWAY

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https://doi.org/10.1038/1921216a0

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