Letter | Published:

Susceptibility of Hamsters to the Oral Administration of Mycobacterium johnei

Nature volume 192, pages 12021203 (23 December 1961) | Download Citation



THE development of a method of counting viable units of bacilli in the tissues of sheep1 has enabled us to re-examine the potentialities of laboratory animals as experimental hosts for M. johnei. The oral route of challenge was chosen because it is the most likely route of infection in naturally occurring Johne's disease. Progressive infection in the tissues after oral dosing was considered to be a better test of the true susceptibility of animals than the direct introduction of bacilli by parenteral methods.

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  1. 1.

    , , and , J. Comp. Path., 71, 286 (1961).

  2. 2.

    , , and , J. Comp. Path., 71, 300 (1961).

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  1. Animal Diseases Research Association, Moredun Institute, Gilmerton, Edinburgh, 9.

    • N. J. L. GILMOUR
    •  & J. G. BROTHERSTON


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