Letter | Published:

Histochemical Localization of Uridine Diphosphoglucose Dehydrogenase in Cartilage

Naturevolume 192pages11991200 (1961) | Download Citation



THIS communication presents a method for the histochemical demonstration of uridine diphospho-glucose dehydrogenase in cartilage. This enzyme system is active in the pathway of synthesis of glucuronic acid1,2.

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  1. 1

    Kalckar, H. M., and Maxwell, E., Physiol. Rev., 38, 77 (1958).

  2. 2

    Roseman, S., Amer. J. Med., 26, 749 (1959).

  3. 3

    Strominger, J. L., Maxwell, E. S., Axelrod, J., and Kalckar, H. M., J. Biol. Chem., 224, 79 (1957).

  4. 4

    Pearse, A. G. E., Histochemistry, Theoretical and Applied, 536 (Little, Brown and Co., Boston, 1960).

  5. 5

    Zimmermann, H., and Pearse, A. G. E., J. Histochem. Cytochem., 7, 271 (1959).

  6. 6

    Strominger, J. L., Kalckar, H. M., Axelrod, J., and Maxwell, E. S., J. Amer. Chem. Soc., 76, 6411 (1954).

  7. 7

    Markovitz, A., Cifonelli, J. A., and Dorfman, A., J. Biol. Chem., 234, 2343 (1959).

  8. 8

    Hambraeus, L., Rodén, L., and Boström, H., Acta Soc. Med. Upsal., 44, 247 (1959).

  9. 9

    Castellani, A. A., De Bernard, B., and Zambotti, V., Nature, 180, 859 (1957).

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  1. KÁROLY BALOGH: Postdoctoral Trainee in Pathology under U.S. Public Health Service Graduate Training Grant.


  1. Department of Pathology, Harvard Medical School and the James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston



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