Letter | Published:

Distribution of Trypsin Inhibitors in the Sera of Various Animals

Nature volume 192, page 1077 (16 December 1961) | Download Citation

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Abstract

TRYPSIN inhibitors have been found in pancreas, serum, colostrum, egg-white, soya bean, and lima bean1. They have all been crystallized except from egg-white2. Thus, examination of the distribution of trypsin inhibitors in proteins of them appears to be out of the question. Recently, Nakamura et al.3 have demonstrated, by two-dimensional paper electrophoresis, that two trypsin inhibitors were contained in the extract of soya-bean. Hence the distribution of trypsin inhibitors in other biological fluids deserves to be re-investigated to see whether there are also two inhibitors in them or not.

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References

  1. 1.

    , and , in The Proteins, 2, 1060 (Acad. Press Inc., New York, 1950). , and , Advances in Protein Chem., 9, 203 (1954).

  2. 2.

    , and , J. Biol. Chem., 235, 1680 (1960).

  3. 3.

    , , , and , Z. physiol. Chem., 318, 115 (1960).

  4. 4.

    , , and , Nature, 188, 144 (1960).

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Author information

Affiliations

  1. Institute for Medical Chemistry, Yamaguchi Medical School, Ube, Japan.

    • S. NAKAMURA
    •  & T. WAKEYAMA

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DOI

https://doi.org/10.1038/1921077a0

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