Removal of Internally Deposited Radionuclides by Triethylenetetraamine-hexaacetic Acid


INCREASING the number of donor groups in chelating agents can give rise to the formation of more stable chelates1–3 and, therefore, to a higher mobilization of internally deposited trivalent and other metal ions of higher valency. This has been demonstrated with ethylenediamine - NNN′N′ - tetraacetic acid (EDTA) and diethylenetriamine-NNN′N′N″-penta-acetic acid (DTPA)4,5, that is, with chelating agents with 6 and 8 donor groups respectively. For this reason extension of this work to the 10-dentate triethylenetetraamine - NNN′ N′ N″ N‴ - hexaacetic acid (TTHA) seemed to be worth while.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Anderegg, G., Nägeli, P., Müller, F., and Schwarzenbach, G., Helv. Chim. Acta, 42, 827 (1959).

  2. 2

    Durham, E. J., and Ryskiewich, D. P., J. Amer. Chem. Soc., 80, 4812 (1958).

  3. 3

    Harder, R., and Chaberek, S., J. Inorg. Nucl. Chem., 11, 197 (1959).

  4. 4

    Heller, H. J., and Catsch, A., Strahlentherapie, 109, 464 (1959).

  5. 5

    Catsch, A., Fed. Proc., Supp. 1961 (in the press), which includes further references.

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

CATSCH, A., SCHINDEWOLF-JORDAN, D. Removal of Internally Deposited Radionuclides by Triethylenetetraamine-hexaacetic Acid. Nature 191, 715 (1961).

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.