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Prevention of Ammonia Toxicity by Amino-acids concerned in the Biosynthesis of Urea

Nature volume 191, pages 705–706 (1961)Cite this article

Abstract

RELATIONSHIPS have been pointed out by several investigators1 between high levels of blood ammonia and various clinical syndromes, for example, some psychoses, mental disturbances associated with heart failure, tumours, jaundices, hepatic encephalopathies, etc. In some cases a reduction in the level of ammonia has resulted in considerable amelioration of these pathological symptoms; the various procedures for this purpose are of considerable interest1.

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Author notes

  1. FRANCESCO SALVATORE

    Present address: Argonne National Laboratory, Division of Biological and Medical Research, 9700 South Cass Avenue, Argonne, Illinois, U.S.A.

Authors and Affiliations

  1. Institute of Biological Chemistry, University of Naples, Via Costantinopoli 16

    FRANCESCO SALVATORE & VINCENZO BOCCHINI

Authors
  1. FRANCESCO SALVATORE
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  2. VINCENZO BOCCHINI
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SALVATORE, F., BOCCHINI, V. Prevention of Ammonia Toxicity by Amino-acids concerned in the Biosynthesis of Urea. Nature 191, 705–706 (1961). https://doi.org/10.1038/191705a0

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