Letter | Published:

An Antigen in Lesions of Molluscum Contagiosum

Naturevolume 191page509 (1961) | Download Citation

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Abstract

OUCHTERLONY'S technique of agar diffusion1 has made it possible to demonstrate the presence of certain viral antigens and antibodies not identifiable by other serological means. Datt and Orleans2, in 1958, found an antigenic substance common to vaccinia and pig pox; Taylor-Robinson and Rundle3 have demonstrated a common antigen in chicken pox and herpes zoster. These successes prompted a re-investigation of the antigenicity of molluscum contagiosum, a large virus that produces benign skin tumours in man.

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References

  1. 1

    Ouchterlony, O., Acta Path. Microbiol. Scand., 25, 186 (1948).

  2. 2

    Datt, N. S., and Orleans, E. S., Immunol., 1, 81 (1958).

  3. 3

    Taylor-Robinson, D., and Rundle, C. J. M., Brit. J. Exp. Path., 40 (5), 517 (1959). Crumpton, M. J., and Davies, D. A. L., Proc. Roy. Soc., B, 145, 109 (1956).

  4. 4

    Mitchell, J. C., Brit. J. Exp. Path., 34, 44 (1953).

  5. 5

    Blank, H., and Rake, G., Viral and Rickettsial Diseases of the Skin, Eye, and Mucous Membranes of Man (Boston: Little, Brown and Co., 1955).

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  1. Division of Dermatology, Department of Medicine, University of California School of Medicine, San Francisco

    • WILLIAM L. EPSTEIN
    • , IRENE P. SENECAL
    •  & ALAN M. MASSING

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https://doi.org/10.1038/191509a0

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