Letter | Published:

Effect of the Bilateral Section of the Splanchnic Nerve on Erythropoiesis

Naturevolume 191pages500501 (1961) | Download Citation



DESPITE much recent work on erythropoietin which has established the important part played by the humoral factor in erythropoiesis, participation of the nervous system in the regulation of erythropoiesis has not been established. In view of the report of Jacobson et al. 1 suggesting the renal production of erythropoietin, as well as the work of Nakayama2 that showed the effect of the bilateral section of splanchnic nerve in abolishing the decrease of renal blood-flow on loss of blood or anoxic anoxia, we performed a bilateral section of splanchnic nerve in rats to observe the effect on erythropoiesis.


  1. 1

    Jacobson, L. O., Goldwasser, E., Fried, W., and Plzak, L., Nature, 179, 633 (1957).

  2. 2

    Nakayama, S., Respiration and Circulation, 7, 191 (1959) (in Japanese).

  3. 3

    Gray, S., and Sterling, K., J. Clin. Invest., 29, 1614 (1950).

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  1. Third Department of Internal Medicine, School of Medicine, University of Tokyo, Bunkyo-ku, Hongo, Tokyo



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