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Abnormal Fœtal Hæmoglobins

Naturevolume 191pages397398 (1961) | Download Citation



DURING the past few years, certain human fœtal hæmoglobin (Hb) variants characterized by electrophoretic mobility different from that of fœtal hæmoglobin have been described. They are: the Hb of Fessas and Papaspyrou1, characterized by mobility at alkaline pH, faster than that of Hb F; Hb Bart's described by Ager and Lehmann2, and also characterized by mobility at alkaline pH faster than that of Hb F ; Hb Alexandra, slower than Hb F, described at the same time by Fessas et al. 3 and by Vella et al. 4.

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  1. 1

    Fessas, Ph., and Papaspyrou, A., Science, 126, 1119 (1957).

  2. 2

    Ager, J. A. M., and Lehmann, H., Brit. Med. J., i, 929 (1958).

  3. 3

    Fessas, Ph., Mastrokalos, N., and Fostiropoulos, G., Nature, 183, 30 (1959).

  4. 4

    Vella, F., Ager, J. A. M., and Lehmann, H., Nature, 183, 30 (1959).

  5. 5

    Fessas, Ph., Brit. Med. J., ii, 886 (1959).

  6. 6

    Vella, F., Nature, 184, 272 (1959).

  7. 7

    Silvestroni, E., Bianco, I., and Muzzolini, M., Policlinico, Sez. Prat., 67, 41 (1960).

  8. 8

    Silvestroni, E., Bianco, I., Muzzolini, M., Modiano, G., and Vallisneri, E., Progr. Med., 13, 705 (1957).

  9. 9

    (a) Ramot, B., Sheba, Ch., Fisher, S., Ager, J. A. M., and Lehmann, H., Brit. Med. J., ii, 1228 (1959). (b) Tuchinda, S., Vareenil, C., Bhanchit, P., and Minnich, V., Pediatrics, 24, 43 (1959). (c) Fessas, Ph., VII Congr. Eur. Soc. Haemat. (London, 1959).

  10. 10

    Hunt, J. A., and Lehmann, H., Nature, 184, 872 (1959).

  11. 11

    Jones, R. E., Schroeder, W. A., Balog, J. E., and Vinograd, J. R., J. Amer. Chem. Soc., 81, 3161 (1959).

  12. 12

    Boyo, A. E., and Hendrickse, R. G., Nature, 184, 997 (1959).

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  1. Istituto d'Igiene dell' Università di Roma, Centro di Studi della Microcitemia e delle Anemie Microcitemiche, Roma

    •  & I. BIANCO


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