Letter | Published:

Quantitative Estimation of Peak Areas in Gas-Liquid Chromatography

Naturevolume 191pages377378 (1961) | Download Citation



QUANTITATIVE estimation of peak areas on gas-liquid chromatograms has been carried out by a variety of methods, which include triangulation, cutting out the peak areas and weighing the cut paper, planimeter tracing and use of an integrator built into the recorder. A new method recently proposed by Bartlet and Smith1 is based on evidence that the peaks obtained with a well-designed chromatograph closely approximate a normal or Gaussian distribution curve.

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  1. 1

    Bartlet, J. C., and Smith, D. M., Canad. J. Chem., 38, 2057 (1960).

  2. 2

    Pecsok, R. L., Principles and Practise of Gas Chromatography, 145 (John Wiley and Sons, Inc., New York, 1959).

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  1. Collip Medical Research Laboratory, University of Western Ontario, London, Ontario

    • K. K. CARROLL


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