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Antibody Response in Rabbits following Injection of Sheep Erythrocytes into Lateral Ventricle of Brain

Abstract

IMMUNOLOGICAL studies of the cerebrospinal fluid have been confined mainly to the passage of antibodies from plasma into the cerebrospinal fluid1. However, the investigation of exchange between cerebrospinal fluid and blood has revealed that various electrolytes2, dyes3 and proteins4 may find their way from cerebrospinal fluid into general circulation. Furthermore, some data5 indicate that red blood cells cross cerebrospinal fluid-blood barrier. It seemed, therefore, advisable to approach the immunological sequences following the injection of heterologous erythrocytes into lateral ventricle of the brain.

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JANKOVIĆ, B., DRAŠKOCI, M. & ISAKOVIĆ, K. Antibody Response in Rabbits following Injection of Sheep Erythrocytes into Lateral Ventricle of Brain. Nature 191, 288–289 (1961). https://doi.org/10.1038/191288b0

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