Letter | Published:

A Positive Feedback Mechanism of Adenosine Triphosphate Synthesis in Erythrocytes

Naturevolume 191pages283284 (1961) | Download Citation

Subjects

Abstract

IN previous papers, Nakao et al.1,2 reported that adenosine triphosphate (ATP) is regenerated in erythrocytes stored for more than several weeks or treated with fluoride3, when the cells are incubated with nucleoside and adenine at 37° C. In these aged or fluoride-treated cells, most of the nucleotides and other acid-soluble phosphate esters were decomposed almost completely and energy metabolism almost entirely stopped. To elucidate the mechanism of adenosine triphosphate synthesis in such erythrocytes, the following observations were carried out :

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Nakao, M., Nakao, T., Tatibana, M., Yoshikawa, H., and Abe, T., J. Biochim. Biophys. Acta, 32, 564 (1959).

  2. 2

    Nakao, M., Nakao, T., Tatibana, M., and Yoshikawa, H., J. Biochem. (Japan), 47, 661 (1960).

  3. 3

    Nakao, M., Nakao, T., and Tamazoe, S., Nature, 187, 946 (1960); J. Biochem. (Japan), 49, 487 (1961).

  4. 4

    Cohn, W. E., and Carter, C. E., J. Amer. Chem. Soc., 72, 4273 (1950).

  5. 5

    Preiss, J., and Handler, P., J. Biol. Chem., 233, 493 (1958).

  6. 6

    Tatibana, M., Nakao, M., and Yoshikawa, H., J. Biochem. (Japan), 45, 1037 (1958).

  7. 7

    Kornberg, A., J. Biol. Chem., 215, 418 (1954).

Download references

Author information

Author notes

    • MAKOTO NAKAO
    •  & TOSHIKO NAKAO

    Present address: Department of Biochemistry, University School of Medicine, Yokohama

Affiliations

  1. Department of Biochemistry, School of Medicine, Gunma University, Maebashi

    • MAKOTO NAKAO
    • , TAKASHI MOTEGI
    • , TOSHIKO NAKAO
    •  & SABURO YAMAZOE
  2. Department of Physiological Chemistry and Nutrition, Faculty of Medicine, University of Tokyo, Tokyo

    • HARUHISA YOSHIKAWA

Authors

  1. Search for MAKOTO NAKAO in:

  2. Search for TAKASHI MOTEGI in:

  3. Search for TOSHIKO NAKAO in:

  4. Search for SABURO YAMAZOE in:

  5. Search for HARUHISA YOSHIKAWA in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/191283a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.