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Occurrence of an Rh-like Antigen in Red Cells of the Sheep

Naturevolume 191page193 (1961) | Download Citation



Landsteiner and Wiener1 discovered that the sera of rabbits immunized by the erythrocytes of the rhesus (macacus) monkey would agglutinate those of certain human subjects irrespective of their ABO groups. They added, therefore, the Rh-antigen to the list of antigens characterizing the human red cells. Some human red cells, therefore, must be assumed to possess a receptor-substance for antibodies which rabbits or still better guinea pigs can form when immunized with rhesus erythrocytes. Later, Wiener and Peters2 demonstrated the anti-genicity of the Rh-receptor of human erythrocytes in man, thus establishing the principal cause for erythroblastosis in the new-born.

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  1. 1

    Landsteiner, K., and Wiener, A. S., Proc. Soc. Exp. Biol. N.Y., 43, 223 (1940).

  2. 2

    Wiener, A. S., and Peters, R. H., Ann. Int. Med., 13, 2306 (1940).

  3. 3

    Fisher, R. A., Ann. Eugen., 13, 150 (1946).

  4. 4

    Fisk, R. T., and Foord, A. G., Amer. J. Clin. Path., 12, 545 (1942).

  5. 5

    Davidsohn, I., and Toharsky, B., Amer. J. Clin. Path., 12, 434 (1942).

  6. 6

    Murray, J., and Clark, E. C., Nature, 169, 886 (1952).

  7. 7

    Urbaschek, B., Z. Immunitätsforsch., 120, 145, 154 (1960).

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  1. Tierhygiene Institut der Universität, Freiburgu i. Br

    •  & K. TRAUTWEIN


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