Abstract
PREVIOUSLY, it has been shown that the catalytic activity of Fe(III) or peroxidase can be enhanced by a variety of colloidal substances including deoxyribonucleic acid1, celluloses2, and starch3. Other investigations4–6 have demonstrated the macromolecular activation or modification of a number of oxidative or hydrolytic systems. Such observations direct attention to the role of environmental factors other than those usually encountered in vitro in biochemical reactions.
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References
- 1
Siegel, S., and Siegel, B. Z., Nature, 179, 421 (1957).
- 2
Goodman, N. S., and Siegel, S., Nature, 184, 53 (1959).
- 3
Siegel, B. Z., and Siegel, S., Nature, 186, 391 (1960).
- 4
Keilin, David, and Hartree, E. F., Biochem. J., 44, 205 (1949).
- 5
Siegel, S., Sub-Cellular Particles (edit. by Hayashi, T., Amer. Physiol. Soc., Washington, 1959).
- 6
Siegel, S., Abstracts, First Intern. Congress of Histochem. and Cytochem. Annales D'Histochimie, 5 (Supplement) 45 (1960).
- 7
Siegel, S., Porto, F., and Frost, P., Arch. Biochem. Biophys., 82, 330 (1959).
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Affiliations
4 Orchard Parkway, White Plains
- B. Z. SIEGEL
Union Carbide Research Institute, White Plains, New York
- S. M. SIEGEL
Department of Biology, Brandeis University, Waltham, Massachusetts
- N. S. GOODMAN
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