Letter | Published:

Regulation of Pyrogallol Oxidations by Alcohols and Sugars

Naturevolume 191pages180181 (1961) | Download Citation



PREVIOUSLY, it has been shown that the catalytic activity of Fe(III) or peroxidase can be enhanced by a variety of colloidal substances including deoxyribonucleic acid1, celluloses2, and starch3. Other investigations4–6 have demonstrated the macromolecular activation or modification of a number of oxidative or hydrolytic systems. Such observations direct attention to the role of environmental factors other than those usually encountered in vitro in biochemical reactions.

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  1. 1

    Siegel, S., and Siegel, B. Z., Nature, 179, 421 (1957).

  2. 2

    Goodman, N. S., and Siegel, S., Nature, 184, 53 (1959).

  3. 3

    Siegel, B. Z., and Siegel, S., Nature, 186, 391 (1960).

  4. 4

    Keilin, David, and Hartree, E. F., Biochem. J., 44, 205 (1949).

  5. 5

    Siegel, S., Sub-Cellular Particles (edit. by Hayashi, T., Amer. Physiol. Soc., Washington, 1959).

  6. 6

    Siegel, S., Abstracts, First Intern. Congress of Histochem. and Cytochem. Annales D'Histochimie, 5 (Supplement) 45 (1960).

  7. 7

    Siegel, S., Porto, F., and Frost, P., Arch. Biochem. Biophys., 82, 330 (1959).

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  1. 4 Orchard Parkway, White Plains

    • B. Z. SIEGEL
  2. Union Carbide Research Institute, White Plains, New York

    • S. M. SIEGEL
  3. Department of Biology, Brandeis University, Waltham, Massachusetts

    • N. S. GOODMAN


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