Letter | Published:

Activity of Glutamic Acid Decarboxylase in Insect Nerve Tissue

Naturevolume 191pages178179 (1961) | Download Citation



As compared with the nerve tissue of mammals, that of insects is known to be particularly rich in acetylcholinesterase1 and in choline-acetylase2. On the other hand, nothing has been reported so far about the occurrence in insects of another enzyme which, in mammals, is characteristic of nerve tissue, namely, glutamic acid decarboxylase. Its reaction product, γ-aminobutyric acid, has been recently found in the free state in bee nerve tissue, in amounts of the same order, on the basis of fresh weight, as in mammalian nerve tissue (Carta, S., and Frontali, N., unpublished work).

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  1. 1

    Metcalf, R. L., and March, R. B., J. Econ. Entomol., 43, 670 (1950).

  2. 2

    Smallman, B. N., J. Physiol., 132, 343 (1956).

  3. 3

    Roberts, E., Younger, F., and Fränkel, S., J. Biol. Chem., 191, 277 (1951).

  4. 4

    Beloff-Chain, A., Catanzaro, R., Chain, E. B., Masi, I., Pocchiari, F., Rossi, C., Proc. Roy. Soc., B, 143, 481 (1955).

  5. 5

    Kolthoff, J. M., and Vleeschhouwer, J. J., Biochem. Z., 189, 191 (1927).

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  1. Istituto Superiore di Sanità, Rome



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