Letter | Published:

Hydrolysis of Fatty Acid Esters of Riboflavin by Pancreatic Lipase

Naturevolume 191pages174175 (1961) | Download Citation



FATTY acid esters of riboflavin, fat-soluble riboflavin derivatives, have been synthesized in our laboratory to widen the application of riboflavin to pharmaceutical and nutritional fields1–3. As a fundamental problem of this application, the possibility of enzymic hydrolysis of these esters to riboflavin and fatty-acids has to be investigated first. This communication deals briefly with their hydrolysis in vitro by pancreatic lipase.

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  1. 1

    Yagi, K., Okuda, J., and Dmitrovskii, A. A., J. Biochem., 48, 621 (1960).

  2. 2

    Yagi, K., Okuda, J., Dmitrovskii, A. A., and Honda, R., vitamins (Japan), 21, 217 (1960).

  3. 3

    Yagi, K., Okuda, J., and Matsubara, T., Vitamins (Japan), 21, 525 (1960).

  4. 4

    Yagi, K., J. Biochem., 43, 635 (1956).

  5. 5

    Reid, R. L., and Lederer, M., Biochem. J., 50, 60 (1951).

  6. 6

    Yagi, K., and Okuda, J., Vitamins (Japan) (in the press).

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  1. Department of Biochemistry, School of Medicine, Nagoya University, Nagoya

    •  & JUN OKUDA


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