Letter | Published:

Structure of Feather Keratin

Naturevolume 191pages171173 (1961) | Download Citation

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Abstract

FEATHER keratin is the outstanding protein fibre structure that still lacks an interpretation generally acceptable in any detail. It has long been known1 that its X-ray diffraction diagram is of a β-type with the strong indication that the residue-length is only about 31/10 Å. instead of the 31/10 Å. and 31/10 Å. found in β-keratin and silk fibroin, and it has corpuscular properties besides2, especially as demonstrated in the paper by Bear and Rugo3, supported also by physico-chemical studies and the finding that the unit is probably a cyclic polypeptide4. In Bear and Rugo's scheme the structure is based on a net of corpuscular units the nodes of which are at approximately (0, 0), (0, ½), (½, ¼), and (½, ¾), the plane of the net containing both the main-chain and side-chain directions. Continuing from this point and associated observations by the same authors, it is the purpose of this communication to state what we believe to be a very strong case for the structure of the corpuscles themselves. The principal steps in the argument may be summarized as follows :

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References

  1. 1

    Astbury, W. T., and Marwick, T. C., Nature, 130, 309 (1932).

  2. 2

    Astbury, W. T., and Lomax, R., Nature, 133, 795 (1934). Ward, W. H., High, L. M., and Lundgren, H. P., J. Polymer Res., 1, 22 (1946).

  3. 3

    Bear, R. S., and Rugo, H. J., Ann. N.Y. Acad. Sci., 53, 627 (1951).

  4. 4

    Woodin, A. M., Biochem. J., 57, 99 (1954); 63, 576 (1956).

  5. 5

    Pauling, L., and Corey, R. B., Proc. U.S. Nat. Acad. Sci., 37, 251 (1951); 37, 729 (1951); 39, 255 (1953).

  6. 6

    Astbury, W. T., J. Text. Inst., 51, P, 515 (1960).

  7. 7

    Astbury, W. T., Ann. Ital. Derm. Sif., Anno 15 (1960).

  8. 8

    Schroeder, W. A., and Kay, L. M., J. Amer. Chem. Soc., 77, 3901 (1955).

  9. 9

    Astbury, W. T., Ninth Procter Memorial Lecture, J. Soc. Leather Trades' Chem. (in the press).

  10. 10

    Ramachandran, G. N., Acta Cryst., 10, 816, (1957); Recent Advances in Gelatin and Glue Research, 32 (Pergamon Press, 1958).

  11. 11

    Fraser, R. D. B., Faraday Soc. Disc. on Spectroscopy, 398 (1950). Ambrose, E. J., and Elliott, A., Proc. Roy. Soc., A, 206, 214 (1951). Bradbury, E. M., Burge, R. E., Randall, J. T., and Wilkinson, G. R., Disc. Farad. Soc., No. 25, 173 (1958). Parker, K. D. (personal communication).

  12. 12

    Fraser, R. D. B., and MacRae, T. P., Text. Res. J., 27, 384 (1952).

  13. 13

    Krimm, S., and Schor, R., J. Phys. Chem., 24, 922 (1956).

  14. 14

    Fräser, R. D. B., and MacRae, T. P., J. Mol. Biol., 1, 387 (1959).

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Affiliations

  1. Department of Biomolecular Structure, University of Leeds

    • W. T. ASTBURY
    •  & E. BEIGHTON

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https://doi.org/10.1038/191171b0

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