Letter | Published:

Some New Esters of Chromone-2-Carboxylic Acid

Naturevolume 191page171 (1961) | Download Citation

Subjects

Abstract

WITH the view of further pharmacological work by one of us (K. V.-B.), it was decided to synthesize certain esters of chromone-2-carboxylic acid, not previously described1–4. The following compounds were obtained : dimethylaminoethyl-chromone-2-carboxylate hydrochloride (Ia), the methiodide of the base (Ib); tropyl-chromone-2-carboxylate (IIa), its hydrochloride (IIb), methobromide (IIc) and methiodide (IId):

References

  1. 1

    Schmutz, J., Lauener, H., Hirt, R., and Sanz, M., Helv. Chim. Acta, 34, 767 (1951).

  2. 2

    Vejdelek, Z. J., Trcka, V., Chyba, O., and Chybova, H., Chem. Listy, 47, 575 (1953); Chem. Abst., 49, 300 (1955).

  3. 3

    Zagorevskii, V. A., Zykov, D. A., and Pronina, L. P., Zhur. Obshchei Khim., 29, 1026 (1959).

  4. 4

    Zagorevskii, V. A., Zykov, D. A., and Vinokurov, V. G., Zhur. Obshchei Khim., 29, 2302 (1959).

  5. 5

    Cramer, F., Papierchromatographie, fourth ed., 164 (Verlag Chemie, Weinheim, 1958).

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Author information

Affiliations

  1. Organic Chemistry Laboratory, Facultad de Quimica

    • JUAN X. DE VRIES
  2. Pharmacology Department, Facultad de Medicina, Montevideo, Uruguay

    • KEMPIS VIDAL-BERETERVIDE

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https://doi.org/10.1038/191171a0

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