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Selenomethionine as an Antioxidant



EVIDENCE has accumulated indicating that: (1) vitamin E functions, at least in part, as a lipid antioxidant; (2) unrelated substances having antioxidant activity can alleviate or prevent some of the symptoms of vitamin E deficiency1; (3) selenium compounds also can alleviate or prevent some of the symptoms of vitamin E deficiency2; (4) the ingestion of selenium oxide renders tissues less susceptible to oxidative attack3; (5) some seleno-amino-acids have antioxidant activity in aqueous lipid emulsions4. The experiments reported here were undertaken to determine whether seleno-amino-acids could act as antioxidants in anhydrous fats and oils.

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  1. 1

    Dam, H., Pharmacol. Rev., 9, 1 (1957).

  2. 2

    Schultze, M. O., in Ann. Rev. Biochem., 29, 391 (1960).

  3. 3

    Bieri, J. G., Dam, H., Prange, I., and Søndergaard, E., Acta physiol. Scand., 52, 36 (1961).

  4. 4

    Zalkin, H., Tappel, A. L., and Jordan, J. P., Arch. Biochem. and Biophys., 91, 117 (1960).

  5. 5

    Denison, jun., G. H., and Condit, P. C., Indust. Eng. Chem., 41, 944 (1949).

  6. 6

    Woodbridge, D. T., M.Sc. Thesis, University of London(1959).

  7. 7

    Painter, E., Chem. Rev., 28, 179 (1941).

  8. 8

    Olcott, H. S., and Einset, E., J. Amer. Oil Chemists Soc., 35, 161 (1958).

  9. 9

    Barnard, D., Bateman, L., Cole, E. R., and Cunneen, J. R., Chem. and Indust., 918 (1958).

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