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Mechanism of Synthesis of Adenine from Hydrogen Cyanide under Possible Primitive Earth Conditions


IT has recently been shown that adenine and the purine precursors 4-aminoimidazole-5-carboxamidine and formamidine are formed spontaneously from hydrogen cyanide in water–ammonia systems under conditions assumed to have existed on the primitive Earth1.

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ORÓ, J. Mechanism of Synthesis of Adenine from Hydrogen Cyanide under Possible Primitive Earth Conditions. Nature 191, 1193–1194 (1961).

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