Letter | Published:

Release of Heparin from the Mast Cells of the Rat

Naturevolume 191page90 (1961) | Download Citation

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Abstract

MAST cells are an important source of tissue heparin and of histamine1,2. Histamine is known to be released following disruption of mast cells3 and in the dog there is an associated release of heparin4. In other animals it has not been possible to detect liberation of heparin coincident with release of histamine.

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References

  1. 1

    West, G. B., Foundation Symposium on Histamine, 14 (Churchill, London, 1956).

  2. 2

    Riley, J. F., The Mast Cells, 72 (Livingstone, London, 1959).

  3. 3

    Archer, G. T., Aust. J. Exp. Biol. Med. Sci., 37, 383 (1959).

  4. 4

    Rocha e Silva, M., Scroggie, A. Evelyn, Fidlar, E., and Jaques, L. B., Proc. Soc. Exp. Biol. Med., 64, 141 (1947).

  5. 5

    Monkhouse, F. C., and Jaques, L. B., J. Lab. Clin. Med., 36, 782 (1950).

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Affiliations

  1. New South Wales Red Cross Blood Transfusion Service, 1 York Street, Sydney

    • G. T. ARCHER

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DOI

https://doi.org/10.1038/191090a0

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