Abstract
MAST cells are an important source of tissue heparin and of histamine1,2. Histamine is known to be released following disruption of mast cells3 and in the dog there is an associated release of heparin4. In other animals it has not been possible to detect liberation of heparin coincident with release of histamine.
Similar content being viewed by others
Article PDF
References
West, G. B., Foundation Symposium on Histamine, 14 (Churchill, London, 1956).
Riley, J. F., The Mast Cells, 72 (Livingstone, London, 1959).
Archer, G. T., Aust. J. Exp. Biol. Med. Sci., 37, 383 (1959).
Rocha e Silva, M., Scroggie, A. Evelyn, Fidlar, E., and Jaques, L. B., Proc. Soc. Exp. Biol. Med., 64, 141 (1947).
Monkhouse, F. C., and Jaques, L. B., J. Lab. Clin. Med., 36, 782 (1950).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ARCHER, G. Release of Heparin from the Mast Cells of the Rat. Nature 191, 90 (1961). https://doi.org/10.1038/191090a0
Issue Date:
DOI: https://doi.org/10.1038/191090a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.