Letter | Published:

Effect of Bradykinin on Uterine Activity

Naturevolume 191page83 (1961) | Download Citation



IT was reported recently1 that plasma kinin is formed spontaneously in human plasma collected during labour. Tested on the isolated rat uterus, the maximum oxytocic activity was stated to be equivalent to several units of oxytocin per millilitre of plasma. It was suggested that kinin formation may be related to the powerful contractions of the human uterus during parturition.

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  1. 1

    Armstrong, D. A. J., and Stewart, J. W., Nature, 188, 1193 (1960).

  2. 2

    Boissonnas, R. A., and Guttmann, St., Jaquenoud, P.-A., Helv. Chim. Acta, 43, 1349 (1960).

  3. 3

    Bainbridge, M. N., Nixon, W. C. W., Schild, H. O., and Smyth, C. N., Brit. Med. J., i, 1133 (1956).

  4. 4

    Smyth, C. N., J. Obstet. Gynæc. Brit. Emp., 64, 59 (1957).

  5. 5

    Caldeyro-Barcia, R., and Poseiro, J. J., Clin. Obstet. and Gynec., 3, 386 (1960).

  6. 6

    Berde, B., and Saameli, K., Acta Endocrinol., 32, 391 (1959).

  7. 7

    Berde, B., Doepfner, W., and Konzett, H., Brit. J. Pharmacol., 12, 209 (1957).

  8. 8

    Rothlin, E., Schweiz. med. Wschr., 68, 971 (1938).

  9. 9

    Konzett, H., and Stürmer, E., Brit. J. Pharmacol., 15, 544 (1960).

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  1. Pharmacological Laboratories, Sandoz, Ltd., Basle

    • B. BERDE
  2. Department of Obstetrics and Gynæcology, Cantonal Hospital, St. Gall, Switzerland

    • K. SAAMELI


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