Karyological Demonstration of Hybridization of Mammalian Cells in vitro

Abstract

IN a recent publication, Barski, Sorieul and Cornefert1 described the formation of cells with a hybrid karyotype in mixed cultures of two mouse cell strains in vitro. The experiments to be described show that this phenomenon is easily reproducible and that it is not limited to a pair of strains of strictly defined karyotypes.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Barski, G., Sorieul, S., and Cornefert, F., C.R. Acad Sci., Paris, 251, 1825 (1960).

  2. 2

    Sanford, K. K., Likely, G. D., and Earle, W. R., J. Nat. Cancer Inst., 15, 215 (1954).

  3. 3

    Chu, E. H. Y., Sanford, K. K., and Earle, W. R., J. Nat. Cancer Inst., 21, 729 (1958).

  4. 4

    Morgan, J. F., Morton, H. J., and Parker, R. C., Proc. Soc. Ext. Biol. Med., 73, 1 (1950).

  5. 5

    Evans, V. J., Bryant, J. C., McQuilkin, W. T., Fioramonti, M. C., Sanford, K. K., Westfall, B. B., and Earle, W. R., Cancer Res., 16, 87 (1956).

  6. 6

    Lederberg, J., J. Cell. and Comp. Physiol., 52, Supp. 1, 383 (1958). Schultz, J., Ann. N.Y. Acad. Sci., 71, (6), 994 (1958).

  7. 7

    Hauschka, T. S., J. Cell. and Comp. Physiol., 52, Supp. 1, 197 (1958).

  8. 8

    Jacob, F., and Wollman, E. L., Ann. Inst. Pasteur, 91, 486 (1956).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

SORIEUL, S., EPHRUSSI, B. Karyological Demonstration of Hybridization of Mammalian Cells in vitro . Nature 190, 653–654 (1961). https://doi.org/10.1038/190653b0

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.