Abstract
ZONE electrophoresis on starch-gel revealed that purified sheep prolactin contained at least four components with crop-sac stimulating activity in the pigeon1. Recently three preparations of purified human growth hormone made by different procedures in different laboratories have been examined by the same method. They all show a striking similarity to sheep prolactin in the mobility and relative amounts of the principal components. This similarity has also been observed by Barrett, Friesen and Astwood2. By contrast the patterns are quite unlike the patterns we have observed with ox, sheep, pig and whale growth hormone.
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References
Ferguson, K. A., and Wallace, A. L. C., Nature (in the press).
Barrett, R. J., Friesen, H., and Astwood, E. B., Federation Proc. (in the press).
Wilhelmi, A. E., Henry Ford Hospital Med. Bull., 7, 2 (1959).
Li, C. H., Symposium on Protein Structure, edit. by Neuberger, A., chapter 18 (Methuen, London, 1959).
Raben, M. S., Recent Progr. Hormone Res., 15, 71 (1959).
Wilhelmi, A. E., Fishman, J. B., and Russell, J. A., J. Biol. Chem., 176, 735 (1948).
Wilhelmi, A. E., Hypophysial Growth Hormone, Nature and Actions, edit. by Smith, R. W., Gaebler, O. H., and Long, C. N. H., 59 (McGraw-Hill, New York, 1955).
Sinkoff, M. W., and De Bodo, R. C., Arch. Exp. Path., Pharmak. 219, 100 (1953).
Knobil, E., and Greep, R. O., Recent Progr. Hormone Res., 15, 1 (1959).
Bergenstal, D. M., and Lipsett, M. B., J. Clin. Invest., 37, 877 (1958).
Riddle, O., and Bates, R. W., Sex and Internal Secretions, edit. by Allen, E., chapter 20, 1088 (Williams and Wilkins, Baltimore, 1939).
Knobil, E., Recent Progr. Hormone Res., 15, 106 (1959).
Wilhelmi, A. E., Ciba Foundation Colloquia on Endocrinology, 13, 25 (1960).
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FERGUSON, K., WALLACE, A. Prolactin Activity of Human Growth Hormone. Nature 190, 632–633 (1961). https://doi.org/10.1038/190632a0
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DOI: https://doi.org/10.1038/190632a0
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