Incorporation of Thymidine into Deoxyribonucleic Acid by Extracts from Bacteria exposed to Ultra-violet Light

Abstract

ULTRA-VIOLET LIGHT induces a lag in the synthesis of deoxyribonucleic (DNA) acid in Escherichia coli 1. After a dose-dependent incubation interval, the irradiated bacteria will resume synthesis at almost the same rate as prior to exposure. Recently, various investigators2–4 have shown that blockage of ribonucleic acid (RNA) or protein synthesis prevents the recovery of DNA synthesis in bacteria irradiated with ultra-violet light. The capacity of the bacteria to synthesize DNA after exposure is regained with the initial doubling of RNA in the culture5.

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DOUDNEY, C., BILLEN, D. Incorporation of Thymidine into Deoxyribonucleic Acid by Extracts from Bacteria exposed to Ultra-violet Light. Nature 190, 545–546 (1961). https://doi.org/10.1038/190545a0

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