Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effect of 9α-Fluoro-11β-hydroxy-17-methyltestosterone (‘Ultandren’) on the Testis of the Immature Rat

Abstract

‘ULTANDREN’ (Ciba, Ltd.) is known to be an extremely potent oral androgen, approximately ten times as effective as methyltestosterone1. In a preliminary investigation of its effects on the testis of the immature rat comparable doses of ‘Ultandren’ (0.05 mgm.) and methyltestosterone ((0.5 mgm.) dissolved in 0.5 ml. polyethylene glycol were administered daily by mouth for 10 days to litters of rats aged 28–31 days. To a third group of litter mate controls 0.5 ml. of polyethylene glycol was administered daily.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Lyster, S. C., Lund, G. H., and Stafford, R. O., Endocrinol., 58, 781 (1956).

    Article  CAS  Google Scholar 

  2. Leblond, C. R., and Clermont, Y., Ann. N.Y. Acad. Sci., 55, 548 (1952).

    Article  ADS  CAS  Google Scholar 

  3. Rubinstein, H. S., and Kurland, A. A., Endocrinol., 28, 495 (1941).

    Article  CAS  Google Scholar 

  4. Ludwig, D. J., Endocrinol., 46, 453 (1950).

    Article  CAS  Google Scholar 

  5. Barraclough, C. A., and Leathem, J. H., Anat. Rec., 134, 239 (1959).

    Article  CAS  Google Scholar 

  6. Wakeling, A., J. Endocrinol., 19, 263 (1959).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

CLEGG, E. Effect of 9α-Fluoro-11β-hydroxy-17-methyltestosterone (‘Ultandren’) on the Testis of the Immature Rat. Nature 190, 542–543 (1961). https://doi.org/10.1038/190542a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/190542a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing