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Pigments of Phoma terrestris Hansen and their Biosynthesis

Abstract

Wright and Schofield1 recently reported the failure of cultures of Phoma terrestris Hansen (from the Centralbureau voor Schimmelcultures, Baarn) to produce the pigment phomazarin2 for which (I) is one of the two suggested structures. In our hands cultures from the same source have given this compound, which agrees well in physical properties with those described by Kögl et al. 2. For reasons which we are unable to define, the same organism grown under the usual conditions2 does not invariably produce the pigment. Like Wright and Schofield1 we have observed cyanodontin (II) as a constituent of the mycelium.

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References

  1. Wright, D. E., and Schofield, K., Nature, 188, 233 (1960).

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  2. Kögl, F., and Sparenburg, J., Rec. Trav. Chim., 59, 1180 (1940). Kögl, F., and Quackenbush, F. W., ibid., 63, 251 (1944). Kögl, F., v. Wessem, G. C., and Eisbach, O. I., ibid., 64, 23 (1945).

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  3. Birch, A. J., Ryan, A. J., and Smith, H., J. Chem. Soc., 4773 (1958).

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BIRCH, A., FRYER, R., THOMSON, P. et al. Pigments of Phoma terrestris Hansen and their Biosynthesis. Nature 190, 441–442 (1961). https://doi.org/10.1038/190441a0

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