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Effects of Maternal Age on the Incidence of Congenital Abnormalities in Mouse and Man

Nature volume 190, pages 1134–1135 (1961)Cite this article

Abstract

THE value of data from laboratory animals for the interpretation of the incidence of congenital abnormalities in human beings was first pointed out some time ago by Wright1. Results I have obtained from a balanced two-point backcross linkage experiment in the mouse have shown an effect of maternal age both on viability and recombination. The purpose of this communication is to present these results and discuss their implications for similar phenomena in human beings.

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Authors and Affiliations

  1. Department of Genetics, University of Cambridge,

    W. F. BODMER

Authors
  1. W. F. BODMER
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BODMER, W. Effects of Maternal Age on the Incidence of Congenital Abnormalities in Mouse and Man. Nature 190, 1134–1135 (1961). https://doi.org/10.1038/1901134a0

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