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Correlation between Ulcerative Colitis and Rh Blood Groups

Abstract

Winstone, Henderson and Brooke1 did not find ulcerative colitis to be correlated with the ABO blood groups, secretor status, or the rhesus factor. Their Rh classification was, however, restricted to rhesus-positive and rhesus-negative, presumably based on the use of an anti-D serum only. When we recently examined 185 patients in whom ulcerative colitis had led to colectomy, we also did not find any particular relation to D status, but did find, considerably to our surprise, a definite correlation with the homozygous CC rhesus type. Using as controls Wiener's series of 1,071 New York Whites2, we obtained the results shown in Table 1.

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References

  1. Winstone, N. E., Henderson, A. J., and Brooke, B. N., Lancet, ii, 64 (1960).

  2. Wiener, A. S., and Gordon, E. B., Amer. J. Clin. Path., 19, 621 (1949).

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BOYD, W., HEISLER, M. & OROWAN, E. Correlation between Ulcerative Colitis and Rh Blood Groups. Nature 190, 1123–1124 (1961). https://doi.org/10.1038/1901123a0

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