Rate of Formation of Atropine in Atropa belladonna Plants


WE have studied the biogenesis of atropine-14C in Atropa belladonna plants by a method which we believe to be novel in this field, but which is comparable with that applied so successfully by Calvin1 to the elucidation of the path of carbon in photosynthesis.

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    Calvin, J. Chem. Soc., 1895 (1956). Calvin et al., J. Amer. Chem. Soc., 78, 4120 (1956).

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    Beal, and Scully, Bot. Gaz., 112, 233 (1950).

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    Cromwell, Biochem. J., 37, 717 (1943) and earlier papers. James, New Phytol., 48, 172 (1949).

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    James, in “The Plant Alkaloids”, edit. by Henry, fourth ed. (Churchill, London, 1949).

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    Diaper, Kirkwood, and Marion, Canad. J. Chem., 29, 964 (1951). Leete, Marion, and Spenser, ibid., 32, 1116 (1954).

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    Robinson, J. Chem. Soc., 111, 876 (1917). cf. Bentley, K. W., in “The Alkaloids, The Chemistry of Natural Products”, 1 (Intersci. Pub., Inc., New York, 1957).

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    Robinson, “Structural Relations of Natural Products” (Oxford, 1955).

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CATCH, J., EVANS, E. Rate of Formation of Atropine in Atropa belladonna Plants. Nature 188, 758–759 (1960). https://doi.org/10.1038/188758a0

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