Hydrogen-bonding in Calcium-deficient Hydroxyapatites


MANY calcium phosphates precipitated from solution give the X-ray diffraction pattern of hydroxyapatite but depart from the ideal stoichiometry, Ca10(PO4)6(OH)2, of this compound. Pure hydroxyapatite can be prepared only under hydrothermal bomb conditions1,2, whereas the appearance of hydroxyapatites with low Ca/P ratio from aqueous preparations seems to be the rule rather than the exception.

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  1. 1

    Hayek, E., Lechtleitner, J., and Böhler, W., Angew. Chem., 67, 326 (1955).

    CAS  Article  Google Scholar 

  2. 2

    Perloff, A., and Posner, A. S., Science, 28, 583 (1956).

    ADS  Article  Google Scholar 

  3. 3

    Posner, A. S., and Perloff, A., J. Res. Nat. Bur. Stand., 58, 279 (1957).

    CAS  Article  Google Scholar 

  4. 4

    Likins, R. C., McCann, H. G., Posner, A. S., and Scott, D. B., J. Biol. Chem., 235, 2152 (1960).

    CAS  PubMed  Google Scholar 

  5. 5

    Kolthoff, I. M., and Sandell, E. B., “Textbook of Quantitative Analysis”, 3rd edit., 345 et seq. (Macmillan Company, New York, 1952).

    Google Scholar 

  6. 6

    Gee, A., and Deitz, V. R., Anal. Chem., 25, 1320 (1953).

    CAS  Article  Google Scholar 

  7. 7

    Saylor, C. P., J. Res. Nat. Bur. Stand., 15, 277 (1935).

    CAS  Article  Google Scholar 

  8. 8

    Lippincott, E. R., Welsh, F. E., and Weir, C. E., Anal. Chem. (in the press).

  9. 9

    Lippincott, E. R., and Schroeder, R., J. Chem. Phys., 23, 1099 (1955).

    ADS  CAS  Article  Google Scholar 

  10. 10

    Posner, A. S., Perloff, A., and Diorio, A. F., Acta Cryst., 11, 308 (1958).

    CAS  Article  Google Scholar 

  11. 11

    Neuman, W. F., and Neuman, M. W., Chem. Revs., 53, 1 (1953).

    CAS  Article  Google Scholar 

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POSNER, A., STUTMAN, J. & LIPPINCOTT, E. Hydrogen-bonding in Calcium-deficient Hydroxyapatites. Nature 188, 486–487 (1960). https://doi.org/10.1038/188486a0

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