Abstract
IN the course of previous investigations, we have observed that when either normal or neoplastic tissues of mouse origin are injected into new-born albino CFN rats (Carworth–Wistar origin) occasional animals will develop a wasting disease characterized by roughened scaly skin, sparse hair growth, failure to gain weight normally, and sometimes actual loss of weight1,2. This condition usually appears during the first 7–14 days of life and many of the animals so afflicted succumb within a few days. Others survive this crisis and live for at least 35 days. Apart from the sparse hair and stunted growth, these survivors are apparently normal.
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References
Thompson, J. S., and Gurney, C. W., Transpl. Bull., 24, 114 (1959).
Thompson, J. S., and Gurney, C. W. (submitted for publication).
Billingham, R. E., and Brent, L., Transpl. Bull., 4, 67 (1957).
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Anderson, N. F., Delorme, E. J., and Woodruff, M. F. A., Transpl. Bull., 25, 93 (1960).
Gengozian, N., J. Immunol., 83, 173 (1959).
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THOMPSON, J., GURNEY, C. Serum Protein Abnormalities in ‘Runted’ Albino Rats. Nature 188, 421–423 (1960). https://doi.org/10.1038/188421a0
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DOI: https://doi.org/10.1038/188421a0
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