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Sodium and Potassium in Mitochondrial Membrane Fractions

Naturevolume 187pages949950 (1960) | Download Citation



IN a preliminary attempt to explain the observations that muscle1 and liver2 mitochondria are able to transport actively potassium but not sodium, the concentrations of these ions in mitochondrial membrane fractions were studied and compared with those in intact mitochondria. The results indicated that the specific activity (µgm. sodium or potassium/mgm. dry weight) of sodium was several times greater in mitochondrial membrane fractions than in intact particles, whereas the reverse was found with potassium.

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  1. FRANK ULRICH: Established Investigator of the American Heart Association.


  1. Department of Physiology, Yale University School of Medicine, New Haven, 11, Conn.



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