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Sodium and Potassium in Mitochondrial Membrane Fractions

Abstract

IN a preliminary attempt to explain the observations that muscle1 and liver2 mitochondria are able to transport actively potassium but not sodium, the concentrations of these ions in mitochondrial membrane fractions were studied and compared with those in intact mitochondria. The results indicated that the specific activity (µgm. sodium or potassium/mgm. dry weight) of sodium was several times greater in mitochondrial membrane fractions than in intact particles, whereas the reverse was found with potassium.

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References

  1. Ulrich, F., Amer. J. Physiol., 197, 997 (1959).

    CAS  PubMed  Google Scholar 

  2. Spector, W. G., Proc. Roy. Soc., B, 141, 268 (1953).

    Article  ADS  CAS  Google Scholar 

  3. Ulrich, F., Amer. J. Physiol., 198, 847 (1960).

    CAS  PubMed  Google Scholar 

  4. Hogeboom, G. H., in “Methods in Enzymology” ed. by S. P. Colowick and N. O. Kaplan, 1, 16 (Academic Press, N.Y., 1955).

    Google Scholar 

  5. Watson, M., and Siekevitz, P., J. Biophys. Biochem. Cytol., 2, 639 (1956).

    Article  CAS  Google Scholar 

  6. McMurray, W. C., Maley, G. F., and Lardy, H. A., J. Biol. Chem., 230, 219 (1958).

    CAS  PubMed  Google Scholar 

  7. Kielley, W. W., and Bronk, J. R., J. Biol. Chem., 230, 521 (1958).

    CAS  PubMed  Google Scholar 

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ULRICH, F. Sodium and Potassium in Mitochondrial Membrane Fractions. Nature 187, 949–950 (1960). https://doi.org/10.1038/187949a0

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