Abstract
A WATER-SOLUBLE, non-viscous form of deoxyribonucleoprotein has been isolated from purified calf thymus nuclei by a process that minimizes enzyme degradation. Previously the only preparation of deoxyribonucleoprotein generally accepted as undegraded has been the fibrous one, forming gels in water and only slightly soluble, with a molecular weight of 17 million1.
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References
Doty, P., and Zubay, G., J. Molecular Biol., 1, 1 (1959).
Dounce, A. L., Witter, R. F., Monty, K. J., Pate, S., and Cottone, M. S., J. Biophys. and Biochem. Cytol., 1, 139 (1955).
Philpot, J.St. L., and Stanier, J. E., Biochem. J., 63, 214 (1956).
Mirsky, A. E., and Pollister, A. W., J. Gen. Physiol., 30, 101 (1946). Frick, G., “Studies on Desoxyribonucleoprotein and Desoxyribonucleic Acid,” dissertation, Uppsala (1954).
Frampton, V. C., J. Biol. Chem., 129, 223 (1939).
Shooter, K. V., and Butler, J. A. V., Trans. Farad. Soc., 52, 734 (1956).
Scheraga, H. A., and Mandelkern, L., J. Amer. Chem. Soc., 71, 536 (1949).
Carter, A. C., J. Amer. Chem. Soc., 63, 1960 (1941).
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WELSH, R. Water-soluble, Non-fibrous Deoxyribonucleoprotein from Calf Thymus Nuclei. Nature 187, 943–944 (1960). https://doi.org/10.1038/187943b0
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DOI: https://doi.org/10.1038/187943b0
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