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Water-soluble, Non-fibrous Deoxyribonucleoprotein from Calf Thymus Nuclei

Abstract

A WATER-SOLUBLE, non-viscous form of deoxyribonucleoprotein has been isolated from purified calf thymus nuclei by a process that minimizes enzyme degradation. Previously the only preparation of deoxyribonucleoprotein generally accepted as undegraded has been the fibrous one, forming gels in water and only slightly soluble, with a molecular weight of 17 million1.

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WELSH, R. Water-soluble, Non-fibrous Deoxyribonucleoprotein from Calf Thymus Nuclei. Nature 187, 943–944 (1960). https://doi.org/10.1038/187943b0

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