Letter | Published:

Water-soluble, Non-fibrous Deoxyribonucleoprotein from Calf Thymus Nuclei

Naturevolume 187pages943944 (1960) | Download Citation

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Abstract

A WATER-SOLUBLE, non-viscous form of deoxyribonucleoprotein has been isolated from purified calf thymus nuclei by a process that minimizes enzyme degradation. Previously the only preparation of deoxyribonucleoprotein generally accepted as undegraded has been the fibrous one, forming gels in water and only slightly soluble, with a molecular weight of 17 million1.

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References

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    Mirsky, A. E., and Pollister, A. W., J. Gen. Physiol., 30, 101 (1946). Frick, G., “Studies on Desoxyribonucleoprotein and Desoxyribonucleic Acid,” dissertation, Uppsala (1954).

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Author notes

  1. RICHARD S. WELSH: Advanced Research Fellow of the American Heart Association.

Affiliations

  1. Chemistry Department, University of Redlands, Redlands, California

    • RICHARD S. WELSH

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DOI

https://doi.org/10.1038/187943b0

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