Letter | Published:

Formation of D-Penicillamine-Cysteine Mixed Disulphide by Reaction of D-Benzylpenicilloic Acid with Cystine

Naturevolume 187pages940941 (1960) | Download Citation

Subjects

Abstract

As part of a study of skin sensitization to benzyl-pencillin, I have investigated, the behaviour of D-benzylpenicilloic acid (4-carboxy-5,5′-dimethyl-α-phenylacetamido-2-thiazolidine acetic acid). This compound was found to give allergic cross-reactions of the contact dermatitis type with both benzylpenicillin and D-penicillamine (unpublished work).

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Tabachnick, M., Eisen, H. N., and Levine, B. B., Nature, 174, 701 (1954).

  2. 2

    Cited in : “Chemistry of Penicillin”, 573 edit. by Clarke, G. T., Johnson, J. R., and Robinson, R. (Princeton Univ. Press, Princeton, N.J., 1948).

  3. 3

    Levine, B. B., Nature, see preceding communication.

Download references

Author information

Author notes

  1. BERNARD B. LEVINE: Dazian Foundation Research Fellow, 1958–59.

Affiliations

  1. Departments of Chemistry and Microbiology, Mount Sinai Hospital, New York, N.Y.

    • BERNARD B. LEVINE

Authors

  1. Search for BERNARD B. LEVINE in:

About this article

Publication history

Issue Date

DOI

https://doi.org/10.1038/187940a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.