MNSs Gene Frequencies in English Blood Donors

Article metrics


ESTIMATES of the MNSs gene frequencies in the English population have been based hitherto on the results of tests with anti-M, -N and -S only1,2. Recently, a supply of the very rare anti-s was made available through the kindness of Dr. J. O'Riordan of Dublin3, and a random series of 1,000 Sutton blood donors was tested with all four antisera. The samples were also tested with anti-Mia, -Vw and -Mg. All were negative with the last two antisera, but one donor was found to be Ms/Ns, Mi(a +) Vw −, and a study of her family showed Mi a to be travelling with Ns. The results of the major grouping tests are given in Table 1.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Race, R. R., and Sanger, R., “Blood Groups in Man”, 51 (1950); 62 (1954); 74 (1958) (Oxford University Press).

  2. 2

    Ikin, E. W., et al., cited by Mourant, A. E., in “The Distribution of the Human Blood Groups”, 358 (Oxford University Press, 1954).

  3. 3

    O'Riordan, J., and Cann, J., Vox Sang., (N.S.), 4, 242 (1959).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

CLEGHORN, T. MNSs Gene Frequencies in English Blood Donors. Nature 187, 701 (1960) doi:10.1038/187701a0

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.