MNSs Gene Frequencies in English Blood Donors

Abstract

ESTIMATES of the MNSs gene frequencies in the English population have been based hitherto on the results of tests with anti-M, -N and -S only^1,2. Recently, a supply of the very rare anti-s was made available through the kindness of Dr. J. O'Riordan of Dublin³, and a random series of 1,000 Sutton blood donors was tested with all four antisera. The samples were also tested with anti-Mi^a, -Vw and -M^g. All were negative with the last two antisera, but one donor was found to be Ms/Ns, Mi(a +) Vw −, and a study of her family showed Mi ^a to be travelling with Ns. The results of the major grouping tests are given in Table 1.