Abstract
FOR some years now virologists have recognized the value of the domestic fowl as a means of obtaining high-titred antisera to viral and rickettsial antigens. Bacteriologists and immunologists have almost invariably preferred the rabbit, consequently little information is available about the responses of fowls to soluble bacterial antigens. While investigating the immunological tolerance of diphtheria alumprecipitated toxoid in the domestic fowl1 I had the opportunity of collecting a limited amount of information about the primary and secondary antibody responses of White Leghorn fowls to both tetanus alumprecipitated toxoid (Wellcome series W6874A) and diphtheria alum-precipitated toxoid (Wellcome series BA6403A) ; though only one dosage of each antigen was used, the results may be of value to other workers.
Similar content being viewed by others
Article PDF
References
Gowland, G., and Oakley, C. L., J. Path. Bact. (in the press).
Romer, P. H., and Sames, T., Z. ImmunForsch., 3, 334 (1909).
Glenny, A. T., and Llewellyn-Jones, Mona, J. Path. Bact., 34, 143 (1931).
Glenny, A. T., and Stevens, Muriel, F., J. Roy. Army Med. Corps, 70, 308 (1938).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GOWLAND, G. Antibody Responses of the Domestic Fowl to Two Soluble Bacterial Antigens. Nature 187, 624 (1960). https://doi.org/10.1038/187624a0
Issue Date:
DOI: https://doi.org/10.1038/187624a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.