Abstract
A REDUCED renal blood flow and glomerular filtration-rate, despite a mean aortic pressure over the filtration-level, is a feature inherent to cardiopulmonary by-pass operations. Yet the maintenance of an adequate renal circulation is of primary importance in preventing ischæmic damage to the kidneys1, and much research has been directed toward this special problem in the use of heart-lung machines. Accurate measurements on the critical flow-rate in various forms of by-pass were recently reported by Morris et al. 2.
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References
Beall, A. C., Cooley, D. A., Morris, G. C., and Moyer, J. H., Ann. Surg., 146, 190 (1957).
Morris, G. C., Awe, W. C., Bender, H. W., Cooley, D. A., and De Bakey, M. E., in “Extracorporeal Circulation”, edit. by Allen, J. G. (Charles C. Thomas, Springfield, Illinois, 1958).
Perkins, H. A., Osborn, J. J., and Gerbode, F., “Extracorporeal Circulation”, edit. by Allen, J. G. (Charles C. Thomas, Springfield, Illinois, 1958).
Sarajas, H. S. S., Kristoffersson, R., and Frick, M. H., Amer. J. Physiol., 197, 1195 (1959).
Despopoulus, A., Fed. Proc., 15, 48 (1956).
Despopoulus, A., and Weissbach, H., Amer. J. Physiol., 189, 548 (1957).
Sullenberger, J. W., Anlyan, W. G., and Weaver, W. T., Surgery, 46, 22 (1959).
Sarajas, H. S. S., and Saure, L., Nature, 185, 768 (1960).
Erspamer, V., Arch. Internat. Pharmacodyn., 93, 293 (1953).
Del Greco, F., Masson, G. M. C., and Corcoran, A. C., Amer. J. Physiol., 187, 509 (1956).
Spinazziola, A. J., and Sherrod, J., J. Pharmacol. and Exp. Therap., 119, 114 (1957).
Schneckloth, R., Page, I. H., Del Greco, F., and Corcoran, A. C., Circulation, 16, 523 (1957).
Watkins, E., in “Extracorporeal Circulation”, edit. by Allen, J. G. (Charles C. Thomas, Springfield, Illinois, 1958).
Dexter, D., Stoner, H. B., and Green, H. N., J. Endocrinol., 11, 142 (1954).
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FRICK, M. Influence of 5-Hydroxytryptamine on Renal Function in Extracorporeal Circulation. Nature 187, 609–610 (1960). https://doi.org/10.1038/187609a0
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DOI: https://doi.org/10.1038/187609a0
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